Skip to main content

Chemotherapeutic Agents Present in Medicinal Plants

Chemotherapeutic agents are the chemicals which are used in the Chemotherapy for the cancer treatment. Chemotherapy involves the use of these chemical agents for the cancer treatment. Plants are the very good source of Chemotherapeutic agents. The proper research on this field involving the use of natural organisms to treat cancer was started in 1950s. Now scientist are working on dozens of plants which can be used to cure that fatal disease. This use of plants to produce Chemotherapeutic agents tells the importance of traditional medicine in our lives which inexpensive as well as no side effects. Following is the list of some very common and useful plants which can be used for this purpose:

Catharanthus roseus


[caption id="attachment_341" align="alignright" width="300"]Catharanthus resous Medicinal Plant for cancer treatment Catharanthus resous
By Pancrat  [GFDL], via Wikimedia Commons[/caption]Leaves of this tropical plant is was initially famous for its anti-diabetic effects but later, Robert L. Noble found two anti-cancer Chemotherapeutic agents in it. These two chemical are alkaloids and almost identical. These  two dimeric terpenoid indole alkaloids, vinblastine and vincristine are widely used in the Chemotherapy. These agents have toxic effects for the tumor cells. Scientist have working on it in vivo and in vitro for further research.

Momordica charantia


[caption id="attachment_369" align="alignright" width="345"]Momordica charantia as anticancer plant Momordica charantia - Rain-Tree.com[/caption]

Bitter melon was also known for anti-diabetic effect. Bitter melon extract (BME) is known for the anticancer effects. Breast cancer is the most major type of cancer in the USA, during the treatment of, women develops resistance against the chemotherapeutic drugs. BME is very good for treating this resistance. BME treatment of breast cancer cells resulted in a significant decrease in cell proliferation and induced apoptotic cell death.Fruther Studies on Momordica charantia proves that this can be a good diet for the prevention and the treatment of the cancer as well:

  • It decrease the cell proliferation and Increase the apoptotic cell death

  • BME treatment enhanced p53, p21, and pChk1/2 and inhibited cyclin B1 and cyclin D1 expression which is a cell cycle regulation mechanism.

Melia azadirachta


[caption id="attachment_371" align="alignright" width="375"]Melia azedarach containg Chemotherapeutic agents Melia azedarach Bugwood[/caption]

12-O-Acetylazedarachin B is the chemotherapeutic agent present in this plant. This chemical works against the leukemia and stomach cancer cell lines. The anti-cancer effect of this chemical is due inducing the apoptosis. Scientist isolated three different steroids from it which target the three different cancer cell lines.

  • A549 - Its the human alveolar adenocarcinoma cell line.

  • H460 - This is the cancer cell line of the lungs

  • U251 - Human glioma (Glima cells of Nervous system) cell line



Labels:

Comments

Post a Comment

Popular posts from this blog

Benefits of Eating Sago

You might be familiar with the little white pearls called "Sago", but you may not know that it's a fruit obtained from Sago Palms. It is cultivated mostly in south-East Asia, especially from Malaysia and Indonesia. Nutritional Value of Sago  It is one of the cheapest staple food and also called complete carbohydrate food.  It contains; 94% of Starch 0.2 gm of protein 0.5 gm dietary fibre   10 ml of calcium 12 ml of iron It is lightweight, easily digestible and suitable food for all groups of ages especially for children, and elders. It is mostly added to dietary blend regimens of the patients specifically to those whose digestive system is weak. It is also beneficial during childbirth because of its multi nutrient content. It is also introduced in the weaning diet of the babies after 8 months due to its softness and easy digestion. Cooking Methods of Sago Sago can be cooked by various methods alone or in combination.  It is mostly used as
1 comment
Read more

How To Start Your Own Backyard Garden from Scratch?

Are you interested in beginning the journey of your own backyard garden? If yes, then don't think too much, believe in yourself because positive thinking leads to positive outcomes.  I f you want to start a  backyard  garden for growing your own vegetables,  you should do it. Don't let that whole useful place go to waste. Gardening has many advantages: it saves money, saves the nature and planet, grows fresh vegetables with interesting flavours. There are 11 steps for beginners who have no idea where to start; Selection of Site The most important step is to choose the right site for a backyard garden. You need a place that gets plenty of sunlight daily, closer  to a source of water, and shielded from frost and wind because many plants  such as  tomatoes  and cucumbers need shelter from the wind.   If there are trees around your selected place,  consider the spread of their roots, you may need to dig a barrier around your garden to block root incursions.  Y ou wil
Post a Comment
Read more

Best Mouth Freshener Spray 2017 - Buyer's Guide and Reviews

Does your mouth stink like garbage or rotten eggs?  Bad smell not only makes you feel embarrassed but make people go away from you. It's inevitable after a drinking party or barbecue night.  Yes! it's natural. But this doesn't mean we can't anything for it. Our mouth is full of bad and bad bacteria. They feed on the food we eat, mucus and the dead cells of our mouth. Bad mouth smell can spoil  your best moments Bad bacteria produce foul smell inside our mouth when they decompose the food for themselves. This smell inside our mouth is usually the by-products of the food they decomposed. Some foods and Drinks also produces smell in your breath like alcohol . 59% of men and 70% of women said they won't date with the partner has bad breath This is the reason why only Americans spent billions of dollars on mouth freshers only.  There are several home remedies for breath freshness. But if you are looking for any mouth freshener buy online then this buyer's guide with
4 comments
Read more